Microenvironment around thiacarbocyanine dyes in lysolecithin micelles, surfactant micelles and lecithin liposomal membranes.

Nature of interaction of dextran sulfate with lecithin dispersions and lysolecithin micelles.

Lecithin and lecithin/cholesterol dispersions as well as lysolecithin micelles were used to provide basic information on the mechanism of the interaction of zwitterionic phospholipids with dextran sulfate. The addition of dextran sulfate to lecithin dispersions or lysolecithin micelles in the presence of Ca2+ produced insoluble complexes. At each Ca2+ concentration, the amount of insoluble comp...

Diffusion of Surfactant Micelles

Therapeutic surfactant-stripped frozen micelles

Injectable hydrophobic drugs are typically dissolved in surfactants and non-aqueous solvents which can induce negative side-effects. Alternatives like 'top-down' fine milling of excipient-free injectable drug suspensions are not yet clinically viable and 'bottom-up' self-assembled delivery systems usually substitute one solubilizing excipient for another, bringing new issues to consider. Here, ...

Brownian dynamics of mixed surfactant micelles.

We investigate micelle formation in a system containing two or more different amphiphiles with different geometries using a stochastic molecular-dynamics (MD) simulation method. For a binary system containing two amphiphiles, we calculate the critical micelle concentration (CMC) and cluster distribution for the mixture at several mole fractions and compare the simulation results with those pred...

Solubilization of Organic Dyes in Surfactant Micelles Master of Science Thesis in the Master Degree Programme Materials and Nanotechnology

In this study, the solubilization of two organic dyes, Sudan I (1-Phenylazo-2-naphtol) and Quinizarin (1,4-Dihydroxyanthraquinone), was studied in the presence of different types of surfactants (2 polymerics, 2 nonionics, 2 anionic, and one cationic) using UV-Vis spectroscopy. The effects of temperature, pH and addition of different electrolytes (NaCl, Na2CO3, NaI, NaOH, NaSCN) on dye solubiliz...